Effect of injectable calcium alginate–amelogenin hydrogel on macrophage polarization and promotion of jawbone osteogenesis

Author:

Zhao Tingting1,Chen Luyuan2,Yu Chengcheng3,He Gang3ORCID,Lin Huajun3,Sang Hongxun4,Chen Zhihui2,Hong Yonglong3,Sui Wen5,Zhao Jianjiang1ORCID

Affiliation:

1. Shenzhen Stomatological Hospital, Southern Medical University, 1092 Jianshe Road, Luohu District, Shenzhen, Guangdong 518001, China

2. Stomatology Center, Shenzhen Hospital, Southern Medical University, 1333 Xinhu Road, Baoan District, Shenzhen, Guangdong 510086, China

3. Department of Maxillofacial Surgery, Shenzhen Hospital, Southern Medical University, 1333 Xinhu Road, Baoan District, Shenzhen, Guangdong 510086, China

4. Shenzhen Key Laboratory of Digital Surgical 3D Printing, Department of Orthopaedics, Shenzhen Hospital, Southern Medical University, 1333 Xinhu Road, Baoan District, Shenzhen, Guangdong, 510086, China

5. College of Stomatology, Shenzhen Technology University, 3002 Lantian Road, Pingshan District, Shenzhen, Guangdong 518118, China

Abstract

Due to persistent inflammation and limited osteogenesis, jawbone defects present a considerable challenge in regenerative medicine.

Funder

Science, Technology and Innovation Commission of Shenzhen Municipality

Basic and Applied Basic Research Foundation of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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