Concomitant inhibition of TLR-4 and SGLT2 by phloretin and empagliflozin prevents diabetes-associated ischemic acute kidney injury
Author:
Affiliation:
1. Laboratory of Molecular Pharmacology, Department of Pharmacy, Birla Institute of Technology and Science Pilani, Pilani Campus, Rajasthan-333031, India
Abstract
Publisher
Royal Society of Chemistry (RSC)
Subject
General Medicine,Food Science
Link
http://pubs.rsc.org/en/content/articlepdf/2023/FO/D3FO01379K
Reference44 articles.
1. Mortality and predictors of acute kidney injury in adults: a hospital-based prospective observational study
2. Acute kidney injury
3. Epigenetic restoration of endogenous Klotho expression alleviates acute kidney injury-diabetes comorbidity
4. Klotho restoration via ACE2 activation: A potential therapeutic strategy against acute kidney injury-diabetes comorbidity
5. TLR4 Signaling Mediates Inflammation and Tissue Injury in Nephrotoxicity
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1. Phloretin as an add-on therapy to losartan attenuates diabetes-induced AKI in rats: A potential therapeutic approach targeting TLR4-induced inflammation;Life Sciences;2023-11
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