Electro-organic synthesis of isatins and hydrazones through C–N cross-coupling and C(sp<sup>2</sup>)–H/C(sp<sup>3</sup>)–H functionalization-Reference-Cited by-同舟云学术

Electro-organic synthesis of isatins and hydrazones through C–N cross-coupling and C(sp²)–H/C(sp³)–H functionalization

Published:2023 Issue:33 Volume:21 Page:6707-6714
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Verma Neetu¹,Tyagi Rajdeep²,Khanna Ashish³,Malviya Manisha¹,Sagar Ram²³^ORCID

Affiliation:

1. Department of Chemistry, IIT (Banaras Hindu University), Varanasi-221005, India

2. Glycochemistry Laboratory, School of Physical Sciences, Jawaharlal Nehru University, New Delhi-110067, India

3. Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi-221005, India

Abstract

An efficient and electro-organic synthetic approach to synthesize isatin (indole-2,3-dione) from 2-aminoacetophenone supported by I2–DMSO through C–N cross-coupling and C(sp2)–H/C(sp3)–H functionalization is reported in this communication.

Funder

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB01128C

Reference41 articles.

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4. Synthesis of Isatin and its derivatives containing heterocyclic compounds

5. Iodine-Catalyzed Intramolecular Oxidative Thiolation of Vinylic Carbon-Hydrogen BondsviaTandem Iodocyclization and Dehydroiodination: Construction of 2-Methylene-3-thiophenones