Advancing microfluidic diagnostic chips into clinical use: a review of current challenges and opportunities-Reference-Cited by-同舟云学术

Advancing microfluidic diagnostic chips into clinical use: a review of current challenges and opportunities

Published:2022 Issue:17 Volume:22 Page:3110-3121
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Iyer Vasant¹^ORCID,Yang Zijian²,Ko Jina³,Weissleder Ralph⁴^ORCID,Issadore David¹³^ORCID

Affiliation:

1. Electrical and Systems Engineering Department, University of Pennsylvania, Philadelphia, Pennsylvania, USA

2. Mechanical Engineering Department, University of Pennsylvania, Philadelphia, Pennsylvania, USA

3. Bioengineering Department, University of Pennsylvania, Philadelphia, Pennsylvania, USA

4. Center for Systems Biology, Massachusetts General Hospital/Harvard Medical School, 185 Cambridge Street, Boston, Massachusetts, USA

Abstract

Microfluidic diagnostic (μDX) technologies miniaturize sensors and actuators to the length-scales that are relevant to biology: the micrometer scale to interact with cells and the nanometer scale to interrogate biology's molecular machinery.

Funder

New Jersey Commission on Brain Injury Research

Pennsylvania Department of Health

Allen Foundation

National Institutes of Health

American Cancer Society

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/LC/D2LC00024E

Reference104 articles.

1. F. E. H.Tay , Microfluidics and BioMEMS applications , Springer , 2002

2. Micromachining a Miniaturized Capillary Electrophoresis-Based Chemical Analysis System on a Chip

3. H.Lee , D.Ham and R. M.Westervelt CMOS biotechnology , Springer , 2007

4. D.Issadore and R. M.Westervelt , Point-of-care Diagnostics on a Chip , Springer Science\and Business Media , 2013

5. Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor

Cited by 13 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Current challenges and future prospects of next-generation microfluidics;Next-Generation Smart Biosensing;2024

2. Label-free approaches for extracellular vesicle detection;iScience;2023-11

3. Brain-derived extracellular vesicles as serologic markers of brain injury following cardiac arrest: A pilot feasibility study;Resuscitation;2023-10

4. iCLOTS: open-source, artificial intelligence-enabled software for analyses of blood cells in microfluidic and microscopy-based assays;Nature Communications;2023-08-18

5. Assessment of stored red blood cells through lab-on-a-chip technologies for precision transfusion medicine;Proceedings of the National Academy of Sciences;2023-07-26