Girard reagent purification coupled with hollow-fiber-based stirring liquid microextraction followed by HPLC with diode array detection for determination of naphthoquinones in Qing Long Yi

Author:

Zhou Yuanyuan1234,Liu Yuxin1234,Yang Bingyou1234,Jiang Yanqiu1234,Wang Xiaoli5234,Liu Chenggang6234,Niu Feng7894,Kuang Haixue1234

Affiliation:

1. College of Pharmacy

2. Heilongjiang University of Chinese Medicine

3. Harbin 150040

4. China

5. College of Adult Education

6. Institute of Basic Medicine

7. Quality Management Department

8. Harbin Pharmaceutical Group Sixth Pharm Factory

9. Harbin 150056

Abstract

Naphthoquinones all with carbonyl groups may react with the Girard reagent to form a water-soluble substance called hydrazone. These denatured naphthoquinones can recover lipid solubility transferred to the organic liquid layer.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

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