One fold, two functions: cytochrome P460 and cytochrome c′-β from the methanotroph Methylococcus capsulatus (Bath)

Author:

Adams Hannah R.1234ORCID,Krewson Callie5678,Vardanega Jenny E.5678,Fujii Sotaro9101112,Moreno Tadeo1234,Chicano Chicano1234,Sambongi Yoshihiro9101112,Svistunenko Dimitri1234ORCID,Paps Jordi1234ORCID,Andrew Colin R.5678ORCID,Hough Michael A.1234ORCID

Affiliation:

1. School of Biological Sciences

2. University of Essex

3. Colchester

4. UK

5. Department of Chemistry and Biochemistry

6. Eastern Oregon University

7. La Grande

8. USA

9. Graduate School of Biosphere Science

10. Hiroshima University

11. Hiroshima

12. Japan

Abstract

Structural and spectroscopic characterisation of cytochrome c-β and cytochrome P460 from M. capsulatus (Bath) reveals highly similar protein folds but very different heme pockets, providing functional insights.

Funder

National Science Foundation

Leverhulme Trust

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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