Functionalized nanohybrids with rod shape for improved chemo-phototherapeutic effect against cancer by sequentially generating singlet oxygen and carbon dioxide bubbles

Author:

Zhang Wei12ORCID,Chen Lu1,Zhang Xianbin2ORCID,Gong Peng2ORCID,Wang Xiyu3,Xu Zhiying1,Nie Ganyu1,Xu Lu1ORCID

Affiliation:

1. School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China

2. Department of General Surgery and Institute of Precision Diagnosis and Treatment of Digestive System Tumors, Carson International Cancer Center, Shenzhen University General Hospital, Shenzhen University, Shenzhen 518060, China

3. School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China

Abstract

Rod-shaped and folate-functionalized nanohybrids are able to generate singlet oxygen and carbon dioxide bubbles and improve chemo-phototherapeutic effect against cancer.

Funder

Department of Education of Liaoning Province

Basic and Applied Basic Research Foundation of Guangdong Province

China Postdoctoral Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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