Synthesis of spiropyrrolidine oxindolesviaAg-catalyzed stereo- and regioselective 1,3-dipolar cycloaddition of indole-based azomethine ylides with chalcones

Author:

Yue Guizhou1234ORCID,Wu Yao1234,Dou Zhengjie1234,Chen Huabao5264ORCID,Yin Zhongqiong7264,Song Xu7264,He ChangLiang7264,Wang Xianxiang1234,Feng Juhua1234,Zhang Zuming1234,Zou Ping1234,Lu Cuifen89104

Affiliation:

1. College of Science

2. Sichuan Agricultural University

3. Ya’an

4. China

5. College of Agricultural Sciences

6. Chengdu

7. College of Veterinary Medicine

8. Hubei Collaborative Innovation Center for Advanced Organochemical Materials & Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules

9. Hubei University

10. Wuhan 430062

Abstract

In excess of 100 new compounds were prepared in moderate to high yields (50–95%) with good to excellent diastereoselectivity (11 : 1 → 20 : 1 dr) by Ag-catalyzed 1,3-dipolar cycloaddition.

Funder

Sichuan Agricultural University

National Natural Science Foundation of China

Natural Science Foundation of Hubei Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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