New phenanthrenequinones from <i>Cymbidium ensifolium</i> roots and their anti-inflammatory activity on lipopolysaccharide-activated BV2 microglial cells-Reference-Cited by-同舟云学术

New phenanthrenequinones from Cymbidium ensifolium roots and their anti-inflammatory activity on lipopolysaccharide-activated BV2 microglial cells

Published:2024 Issue:39 Volume:14 Page:28390-28400
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Thant May Thazin¹,Hasriadi Hasriadi²,Poldorn Preeyaporn³,Jungsuttiwong Siriporn⁴^ORCID,Rojsitthisak Pornchai⁵⁶^ORCID,Böttcher Chotima⁷,Towiwat Pasarapa²⁸^ORCID,Sritularak Boonchoo¹⁵^ORCID

Affiliation:

1. Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand

2. Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand

3. Hong Kong Quantum AI Laboratory, Ltd., Hong Kong, 999077, China

4. Department of Chemistry, Center of Excellence for Innovation in Chemistry, Faculty of Science, Ubon Ratchathani University, Ubon Ratchathani 34190, Thailand

5. Center of Excellence in Natural Products for Ageing and Chronic Diseases, Chulalongkorn University, Bangkok, 10330, Thailand

6. Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand

7. Experimental and Clinical Research Center, A Cooperation Between the Max Delbrück Center for Molecular Medicine in the Helmholtz Association and Charité – Universitätsmedizin Berlin, Berlin 13125, Germany

8. Animal Models of Chronic Inflammation-associated Diseases for Drug Discovery Research Unit, Chulalongkorn University, Bangkok, 10330, Thailand

Abstract

The roots of Cymbidium ensifolium yielded a total of 17 compounds, comprising two new compounds (1–2), one new natural product (3), and 14 known compounds (4–17).

Funder

Chulalongkorn University

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA04761C

Reference43 articles.

1. Anti-neuro-inflammatory effects of the bioactive compound capsaicin through the NF-κB signaling pathway in LPS-stimulated BV2 microglial cells

2. Anti-inflammatory effects and antioxidant activity of dihydroasparagusic acid in lipopolysaccharide-activated microglial cells

3. Curcumin attenuates the release of pro-inflammatory cytokines in lipopolysaccharide-stimulated BV2 microglia

4. Anti-inflammatory Activity of a Honey Flavonoid Extract on Lipopolysaccharide-Activated N13 Microglial Cells

5. Hispidulin Inhibits Neuroinflammation in Lipopolysaccharide-Activated BV2 Microglia and Attenuates the Activation of Akt, NF-κB, and STAT3 Pathway