Neuroprotective effect of apigenin against hypoxic-ischemic brain injury in neonatal rats via activation of the PI3K/Akt/Nrf2 signaling pathway
Author:
Affiliation:
1. Department of Neonatology
2. The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University
3. Wenzhou
4. China
5. The University of Illinois at Chicago
6. College of Pharmacy
7. USA
Abstract
Neonatal hypoxic-ischemic (HI) brain injury can lead to mortality and severe long-term disabilities including cerebral palsy and brain injury.
Funder
National Natural Science Foundation of China
Beijing Medical and Health Foundation
Wenzhou Municipal Science and Technology Bureau
Publisher
Royal Society of Chemistry (RSC)
Subject
General Medicine,Food Science
Link
http://pubs.rsc.org/en/content/articlepdf/2021/FO/D0FO02555K
Reference51 articles.
1. Preferential Cephalic Redistribution of Left Ventricular Cardiac Output during Therapeutic Hypothermia for Perinatal Hypoxic-Ischemic Encephalopathy
2. Hypoxic-Ischemic Encephalopathy
3. Current and Experimental Pharmacological Approaches in Neonatal Hypoxic- Ischemic Encephalopathy
4. Mild hypothermia via selective head cooling as neuroprotective therapy in term neonates with perinatal asphyxia: an experience from a single neonatal intensive care unit
5. Two-Year Neurodevelopmental Outcomes After Mild Hypoxic Ischemic Encephalopathy in the Era of Therapeutic Hypothermia
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