Construction of diverse spirooxindoles via a domino reaction of arylamines, but-2-ynedioates and 3-hydroxy-3-(indol-3-yl)indolin-2-ones

Author:

Zhu Ling-Yun1,Sun Jing1,Liu Dan1,Yan Chao-Guo1ORCID

Affiliation:

1. College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002, China

Abstract

An iodine-promoted domino reaction of arylamines/benzylamines, dialkyl but-2-ynedioates and 3-hydroxy-3-(indol-3-yl)indolin-2-ones afforded different spirooxindole derivatives depending on the electronic effect and the position of the substituents.

Funder

Yangzhou University

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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