A cascade signal-amplified fluorescent biosensor combining APE1 enzyme cleavage-assisted target cycling with rolling circle amplification

Author:

Liu Zirui1,Yang Hongqun1,Zhang Beibei1,Li Xinhao1,Wang Hong1,Zhang Yingwei1ORCID

Affiliation:

1. State Key Laboratory of Chemical Resource Engineering, College of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China

Abstract

A cascade signal-amplified fluorescent biosensor was developed by combining APE1 enzyme-assisted target recycling and rolling circle amplification strategy, presenting high sensitivity, excellent specificity and anti-interference ability.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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