Norwilsonnol A, an immunosuppressive polycyclic polyprenylated acylphloroglucinol with a spiro[5-oxatricyclo[6.4.0.03,7]dodecane-6′,1-1′,2′-dioxane] system from Hypericum wilsonii-Reference-Cited by-全球学者库

Norwilsonnol A, an immunosuppressive polycyclic polyprenylated acylphloroglucinol with a spiro[5-oxatricyclo[6.4.0.03,7]dodecane-6′,1-1′,2′-dioxane] system from Hypericum wilsonii

Published:2021 Issue:10 Volume:8 Page:2280-2286
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Xie Shuangshuang¹²³⁴⁵,Zhou Yuan¹²³⁴⁵^ORCID,Tan Xiaosheng⁶⁷³⁴⁵,Sun Weiguang¹²³⁴⁵,Duan Yulin¹²³⁴⁵,Feng Hao⁶⁷³⁴⁵,Sun Lingjuan⁶⁷³⁴⁵,Guo Yi¹²³⁴⁵,Shi Zhengyi¹²³⁴⁵,Hao Xincai⁸⁹¹⁰¹¹¹²,Chen Gang⁶⁷³⁴⁵,Qi Changxing¹²³⁴⁵,Zhang Yonghui¹²³⁴⁵^ORCID

Affiliation:

1. Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation

2. School of Pharmacy

3. Tongji Medical College

4. Huazhong University of Science and Technology

5. Wuhan 430030

6. Institute of Organ Transplantation

7. Tongji Hospital

8. Hubei Key Laboratory of Wudang Local Chinese Medicine Research

9. Hubei Engineering Technology Center for Comprehensive Utilization of Medicinal Plants

10. College of Pharmacy

11. Hubei University of Medicine

12. Shiyan 442000

Abstract

Norwilsonnol A (1), a structurally complex polycyclic polyprenylated acylphloroglucinol (PPAP) bearing an unprecedented scaffold, together with a new biosynthetic analogue, norwilsonnol B (2), were isolated from Hypericum wilsonii.

Funder

Changjiang Scholar Program of Chinese Ministry of Education

National Science Fund for Distinguished Young Scholars

National Science and Technology Program during the Twelfth Five-year Plan Period

Innovative Research Group Project of the National Natural Science Foundation of China

National Natural Science Foundation of China

Huazhong University of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

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