Reductive microenvironment responsive gadolinium-based polymers as potential safe MRI contrast agents
Author:
Affiliation:
1. Huaxi MR Research Center (HMRRC)
2. Department of Radiology
3. West China Hospital
4. and National Engineering Research Center for Biomaterials
5. Sichuan University
6. Amgen Bioprocess Centre
7. Keck Graduate Institute
8. USA
Abstract
A ROX and enzyme-responsive biodegradable gadolinium-based mCA was prepared, demonstrating a short gadolinium retention time and sufficient MRI contrast efficacy in tumors.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering
Link
http://pubs.rsc.org/en/content/articlepdf/2019/BM/C8BM01103F
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