Fluorescent naphthalimide boronates as theranostics: structural investigations, confocal fluorescence and multiphoton fluorescence lifetime imaging microscopy in living cells-Reference-Cited by-同舟云学术

Fluorescent naphthalimide boronates as theranostics: structural investigations, confocal fluorescence and multiphoton fluorescence lifetime imaging microscopy in living cells

Published:2023 Issue:12 Volume:4 Page:1082-1095
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

Green Megan J.¹,Ge Haobo¹,Flower Stephen E.¹,Pourzand Charareh²³,Botchway Stanley W.⁴,Wang Hui-Chen¹,Kuganathan Navaratnarajah⁵,Kociok-Köhn Gabriele¹⁶^ORCID,Li Meng¹⁷,Xu Suying¹⁸^ORCID,James Tony D.¹^ORCID,Pascu Sofia I.¹³^ORCID

Affiliation:

1. Department of Chemistry, University of Bath, Calverton Down, Bath, BA2 7AY, UK

2. Department of Life Sciences, University of Bath, BA2 7AY, UK

3. Centre for Therapeutic Innovation, University of Bath, BA2 7AY, UK

4. STFC Research Complex at Harwell, Rutherford Appleton Laboratory, Harwell Science and Innovation Campus, Harwell, Oxfordshire OX11 0QX, UK

5. Department of Materials, Imperial College London, London, SW7 2AZ, UK

6. Materials and Chemical Characterisation Facility (MC2), University of Bath, Calverton Down, Bath, BA2 7AY, UK

7. State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, P. R. China

8. Hebei Key Lab of Power Plant Flue Gas Multi-Pollutants Control, Department of Environmental Science and Engineering, North China Electric Power University, Baoding 071003, P. R. China

Abstract

New design and synthetic strategies were developed to generate functional phenyl boronic acid-based fluorescent probes with a 1,8-naphthylimide bright core, and their beta-d-glucan hybrids. These were monitored by MP FLIM for their ability to report changes in their environments in live cells.

Funder

Engineering and Physical Sciences Research Council

Science and Technology Facilities Council

European Research Council

Technology Strategy Board

Royal Society

Publisher

Royal Society of Chemistry (RSC)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Molecular Biology,Biochemistry,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CB/D3CB00112A

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