Multifunctional coatings that mimic the endothelium: surface bound active heparin nanoparticles with in situ generation of nitric oxide from nitrosothiols
Author:
Affiliation:
1. National Engineering Research Center for Biomaterials
2. Sichuan University
3. Chengdu 610064
4. China
5. The Institute of Biomaterials and Surface Engineering
6. Southwest Jiaotong University
7. Chengdu 610031
Abstract
Multifunctional coatings that mimic the endothelial function in terms of nitric oxide generation and membrane-bound active heparin species are prepared via the immobilization of cystamine-modified heparin/polyethyleneimine (Hep-Cys/PEI) nanoparticles.
Funder
National Natural Science Foundation of China
China Postdoctoral Science Foundation
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering,General Chemistry,General Medicine
Link
http://pubs.rsc.org/en/content/articlepdf/2018/TB/C8TB00596F
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