Drug -driven self-assembly of pH-sensitive nano-vesicles with high loading capacity and anti-tumor efficacy-Reference-Cited by-全球学者库

Drug -driven self-assembly of pH-sensitive nano-vesicles with high loading capacity and anti-tumor efficacy

Published:2021 Issue:9 Volume:9 Page:3348-3361
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Zhai Yaomin¹²³⁴⁵,Wang Juan¹²³⁴⁵,Qiu Liyan¹²³⁴⁵^ORCID

Affiliation:

1. Ministry of Education (MOE)

2. Key Laboratory of Macromolecular Synthesis and Functionalization

3. Department of Polymer Science and Engineering

4. Zhejiang University

5. Hangzhou 310027

Abstract

A pH-sensitive nano-vesicle was constructed by the drug-driven self-assembly of the amphiphilic copolymer PAP, which displayed a high drug loading capability of 35.77 wt% DOX·HCl and high tumor growth inhibition rate of up to 82.4% in mice.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D0BM01987A

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