Membrane permeabilization can be crucially biased by a fusogenic lipid composition – leaky fusion caused by antimicrobial peptides in model membranes-Reference-Cited by-同舟云学术

Membrane permeabilization can be crucially biased by a fusogenic lipid composition – leaky fusion caused by antimicrobial peptides in model membranes

Published:2023 Issue:16 Volume:19 Page:2919-2931
ISSN:1744-683X
Container-title:Soft Matter
language:en
Short-container-title:Soft Matter

Author:

Beck Katharina¹,Nandy Janina¹,Hoernke Maria¹^ORCID

Affiliation:

1. Chemistry and Pharmacy, Albert-Ludwigs-Universität, Freiburg i. Br., Germany

Abstract

Systematic variation of vesicle lipid composition shows that PE-lipids enhance leaky fusion, an effect potentially causing misinterpretation regarding antimicrobial activity.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SM/D2SM01691E

Reference66 articles.

1. Mode of action of membrane active antimicrobial peptides

2. Evidence for a Novel Mechanism of Antimicrobial Action of a Cyclic R-,W-Rich Hexapeptide

3. Mechanistic Landscape of Membrane-Permeabilizing Peptides

4. The Mechanism of Membrane Permeabilization by Peptides: Still an Enigma

5. Leaky membrane fusion: an ambivalent effect induced by antimicrobial polycations

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