Additive manufacturing of barium-doped calcium silicate/poly-ε-caprolactone scaffolds to activate CaSR and AKT signalling and osteogenic differentiation of mesenchymal stem cells

Author:

Chiu Yung-Cheng12,Lin Yen-Hong3,Chen Yi-Wen34,Kuo Ting-You4,Shie Ming-You356ORCID

Affiliation:

1. School of Medicine, China Medical University, Taichung 406040, Taiwan

2. Department of Orthopedic Surgery, China Medical University Hospital, Taichung 404332, Taiwan

3. x-Dimension Center for Medical Research and Translation, China Medical University Hospital, Taichung 404332, Taiwan

4. Graduate Institute of Biomedical Sciences, China Medical University, Taichung 406040, Taiwan

5. School of Dentistry, China Medical University, Taichung 406040, Taiwan

6. Department of Bioinformatics and Medical Engineering, Asia University, Taichung 41354, Taiwan

Abstract

3D-printed barium-doped calcium silicate/poly-ε-caprolactone scaffold enhanced bone regeneration via activated CaSR and AKT signalling.

Funder

Ministry of Science and Technology, Taiwan

China Medical University Hospital

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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