Role of Quorum Quenching in Pathogen Control in Aquaculture

Abstract

Aquaculture is a rapidly growing sector that provides a substantial portion of the world’s seafood supply. Despite its many benefits, the intensive culture of aquatic animals is also associated with the emergence and spread of bacterial diseases that can result in severe economic losses. Aquatic pathogens, especially bacteria, can proliferate in aquaculture systems, leading to decreased growth, increased mortality and a decrease in the overall health of aquatic organisms. Conventional methods of pathogen control in aquaculture, such as antibiotics, vaccines and disinfectants, have limitations due to the development of antibiotic resistance, vaccine failure and environmental concerns. Therefore, there is a need for alternative strategies that are effective, sustainable and environmentally friendly. One such approach is quorum quenching (QQ), which has the potential to control bacterial infections in aquaculture. This review aims to discuss the role of QQ in pathogen control in aquaculture. The review begins by defining quorum sensing (QS) and QQ and then explores the mechanisms of QQ. It then discusses the application of QQ in aquaculture and concludes with future perspectives on QQ in aquaculture.