Impact of morphological features and chemical composition of tendon biomimetic scaffolds on immune recognition <i>via</i> Toll-like receptors-Reference-Cited by-同舟云学术

Impact of morphological features and chemical composition of tendon biomimetic scaffolds on immune recognition via Toll-like receptors

Published:2024 Issue:18 Volume:12 Page:4695-4712
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Gil-Cantero Sara¹²^ORCID,Iorio Francesco²^ORCID,Unalan Irem²,Kurtuldu Fatih³^ORCID,Künig Sarojinidevi¹,Wenhardt Claus¹,Pinnaro′ Veronica¹,Aigner-Radakovics Katharina¹,Steinberger Peter¹,Boccaccini Aldo R.²^ORCID,Stöckl Johannes¹^ORCID

Affiliation:

1. Center for Pathophysiology, Infectiology and Immunology, Institute of Immunology, Medical University of Vienna, Vienna, Austria

2. Institute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, Germany

3. FunGlass, Alexander Dubček University of Trenčín, Trenčín, Slovakia

Abstract

This work demonstrates that scaffolds’ fiber alignment has an impact on the immune recognition of the scaffolds and presents TLR reporter cells as a simple and fast read out system for analyzing the recognition of the scaffolds by TLRs.

Funder

Horizon 2020 Framework Programme

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/BM/D4BM00147H

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