Design of potent Mincle signalling agonists based on an alkyl β-glucoside template-Reference-Cited by-同舟云学术

Design of potent Mincle signalling agonists based on an alkyl β-glucoside template

Published:2020 Issue:31 Volume:56 Page:4292-4295
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Smith Dylan G. M.¹²³⁴,Hosono Yuki⁵⁶⁷⁸⁹,Nagata Masahiro⁵⁶⁷⁸⁹,Yamasaki Sho⁵⁶⁷⁸⁹,Williams Spencer J.¹²³⁴^ORCID

Affiliation:

1. School of Chemistry and Bio21 Molecular Science and Biotechnology Institute

2. University of Melbourne

3. Vic

4. Australia

5. Department of Molecular Immunology

6. Immunology Frontier Research Center

7. Osaka University

8. Osaka 565-0871

9. Japan

Abstract

Potent signalling agonists of the innate immune receptor Mincle were developed that can be easily prepared from the surfactants octyl and lauryl β-d-glucoside.

Funder

Australian Research Council

Japan Agency for Medical Research and Development

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/CC/D0CC00670J

Reference33 articles.

1. MCL and Mincle: C-Type Lectin Receptors That Sense Damaged Self and Pathogen-Associated Molecular Patterns

2. Sensing Lipids with Mincle: Structure and Function

3. Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

4. Cutting Edge: Mincle Is Essential for Recognition and Adjuvanticity of the Mycobacterial Cord Factor and its Synthetic Analog Trehalose-Dibehenate

5. Mincle is an ITAM-coupled activating receptor that senses damaged cells

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