On the potential of natural products in the discovery of pharma leads: A case for reassessment
Author:
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2010/NP/C003211P
Reference5 articles.
1. Discovery of (E)-9,10-Dehydroepothilones through Chemical Synthesis: On the Emergence of 26-Trifluoro-(E)-9,10-dehydro-12,13-desoxyepothilone B as a Promising Anticancer Drug Candidate
2. Therapeutic effect against human xenograft tumors in nude mice by the third generation microtubule stabilizing epothilones
3. The Total Synthesis of (+)-Migrastatin
4. Diverted Total Synthesis Leads to the Generation of Promising Cell-Migration Inhibitors for Treatment of Tumor Metastasis: In vivo and Mechanistic Studies on the Migrastatin Core Ether Analog
5. Small Molecule Natural Products in the Discovery of Therapeutic Agents: The Synthesis Connection
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