Exploiting thiol-functionalized benzosiloxaboroles for achieving diverse substitution patterns – synthesis, characterization and biological evaluation of promising antibacterial agents-Reference-Cited by-同舟云学术

Exploiting thiol-functionalized benzosiloxaboroles for achieving diverse substitution patterns – synthesis, characterization and biological evaluation of promising antibacterial agents

Published:2024 Issue:5 Volume:15 Page:1751-1772
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Nowicki Krzysztof¹^ORCID,Krajewska Joanna²^ORCID,Stępniewski Tomasz M.³,Wielechowska Monika¹,Wińska Patrycja¹,Kaczmarczyk Anna¹,Korpowska Julia¹,Selent Jana³^ORCID,Marek-Urban Paulina H.¹,Durka Krzysztof¹^ORCID,Woźniak Krzysztof⁴^ORCID,Laudy Agnieszka E.²,Luliński Sergiusz¹^ORCID

Affiliation:

1. Faculty of Chemistry, Warsaw University of Technology, Noakowskiego 3, 00-664 Warsaw, Poland

2. Department of Pharmaceutical Microbiology and Bioanalysis, Medical University of Warsaw, Banacha 1b, 02-097, Warsaw, Poland

3. GPCR Drug Discovery Lab, Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Medical Research Institute (IMIM) – Department of Medicine and Life Sciences, Pompeu Fabra University (UPF), Carrer del Dr. Aiguader, 88, 08003 Barcelona, Spain

4. Faculty of Chemistry, University of Warsaw, Pasteura 1, 00-093 Warsaw, Poland

Abstract

A series of new benzosiloxaboroles with diverse substitution patterns were synthesized from simple SH-substituted precursors followed by comprehensive characterization and evaluation as promising antibacterial agents.

Funder

Narodowe Centrum Nauki

Europäischer Sozialfonds

Horizon 2020 Framework Programme

Institut Hospital del Mar d'Investigacions Mèdiques

Universitat Pompeu Fabra

Politechnika Warszawska

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/MD/D4MD00061G

Reference92 articles.

1. Synthesis and structure of benzoboroxoles: novel organoboron heterocycles

2. The unique chemistry of benzoxaboroles: Current and emerging applications in biotechnology and therapeutic treatments

3. Recent Developments in the Chemistry and Biological Applications of Benzoxaboroles

4. Benzoxaborole compounds for therapeutic uses: a patent review (2010- 2018)

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