Simultaneous tracking of autophagy and oxidative stress during stroke with an ICT-TBET integrated ratiometric two-photon platform

Author:

Hu Wei1,Qiang Taotao1ORCID,Chai Li2,Liang Tianyu1,Ren Longfang1,Cheng Fei1,Li Chunya2ORCID,James Tony D.34ORCID

Affiliation:

1. College of Bioresources and Materials Engineering, Shaanxi Collaborative Innovation Center of Industrial Auxiliary Chemistry & Technology, Shaanxi University of Science & Technology, Xi'an, 710021, China

2. Key Laboratory of Analytical Chemistry of the State Ethnic Affairs Commission, College of Chemistry and Material Science, South-Central University for Nationalities, Wuhan, 430074, China

3. Department of Chemistry, University of Bath, Bath, BA27AY, UK

4. School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang 453007, China

Abstract

Ratiometric simultaneous tracking of autophagy and oxidative stress was achieved using an ICT-TBET integrated platform. Mito-ONOO exhibited excellent selectivity, good chemical stability, and non-overlapping ratiometric signals.

Funder

Henan Normal University

National Natural Science Foundation of China

Natural Science Foundation of Hubei Province

Scientific Research Plan Projects of Shaanxi Education Department

Shaanxi Science and Technology Co-ordination and Innovation Project of China

Shaanxi Province Key R&D Program

Shaanxi Key Science and Technology Innovation Team Project

Hubei Province Technological Innovation Major Project

Young Talent Support Program of Shaanxi Province University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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