Glycyrrhizin inhibits osteoarthritis development through suppressing the PI3K/AKT/NF-κB signaling pathway in vivo and in vitro
Author:
Affiliation:
1. Department of Orthopaedic surgery
2. The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University
3. Wenzhou
4. China
5. Zhejiang Provincial Key Laboratory of Orthopaedics
Abstract
Osteoarthritis (OA) is a serious and frequently occurring disease in the elderly, characterized by cartilage degeneration and proliferation of bone structure.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Zhejiang Province
Publisher
Royal Society of Chemistry (RSC)
Subject
General Medicine,Food Science
Link
http://pubs.rsc.org/en/content/articlepdf/2020/FO/C9FO02241D
Reference38 articles.
1. Osteoarthritis
2. Pathogenesis and management of pain in osteoarthritis
3. Projections of US prevalence of arthritis and associated activity limitations
4. Quantitative histologic analyses of articular cartilage and subchondral bone from osteoarthritic and normal human hips
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