The genus Micromonospora as a model microorganism for bioactive natural product discovery

Author:

Hifnawy Mohamed S.12345,Fouda Mohamed M.12675,Sayed Ahmed M.12675,Mohammed Rabab12875,Hassan Hossam M.12875ORCID,AbouZid Sameh F.12875,Rateb Mostafa E.12875,Keller Alexander910111213ORCID,Adamek Martina1415161317,Ziemert Nadine1415161317ORCID,Abdelmohsen Usama Ramadan1218195ORCID

Affiliation:

1. Department of Pharmacognosy

2. Faculty of Pharmacy

3. Cairo University

4. Cairo

5. Egypt

6. Nahda University

7. Beni-Suef

8. Beni-Suef University

9. Center for Computational and Theoretical Biology

10. Biocenter

11. University of Würzburg

12. 97074 Würzburg

13. Germany

14. Interfaculty Institute of Microbiology and Infection Medicine Tübingen

15. University of Tübingen

16. Tübingen

17. German Centre for Infection Research (DZIF)

18. Minia University

19. 61519 Minia

Abstract

We explore the genus Micromonospora as a model for natural product research and the discovery progress from the classical bioassay-guided approaches through to the application of genome mining and genetic engineering techniques that target specific products.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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