Bergamottin promotes osteoblast differentiation and bone formation via activating the Wnt/β-catenin signaling pathway

Author:

Wang Xue1,Tian Ye1ORCID,Liang Xuechao1,Yin Chong23,Huai Ying1,Zhao Yipu1,Huang Qian1,Chu Xiaohua1,Wang Weisi4,Qian Airong1ORCID

Affiliation:

1. Lab for Bone Metabolism, Xi'an Key Laboratory of Special Medicine and Health Engineering, Key Lab for Space Biosciences and Biotechnology, Research Center for Special Medicine and Health Systems Engineering, NPU-UAB Joint Laboratory for Bone Metabolism, School of Life Sciences, Northwestern Polytechnical University, Xi'an, Shaanxi, 710072, China

2. Department of Clinical Laboratory, Academician (expert) workstation, Lab of epigenetics and RNA therapy, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China

3. Department of Laboratory Medicine, Translational Medicine Research Center, North Sichuan Medical College, Nanchong, Sichuan, China

4. National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai 200025, China

Abstract

Bergamottin promotes osteoblast differentiation and enhances bone formation by activating the Wnt/β-catenin signaling pathway.

Funder

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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