β(2 → 1)-β(2 → 6) branched graminan-type fructans and β(2 → 1) linear fructans impact mucus-related and endoplasmic reticulum stress-related genes in goblet cells and attenuate inflammatory responses in a fructan dependent fashion-Reference-Cited by-同舟云学术

β(2 → 1)-β(2 → 6) branched graminan-type fructans and β(2 → 1) linear fructans impact mucus-related and endoplasmic reticulum stress-related genes in goblet cells and attenuate inflammatory responses in a fructan dependent fashion

Published:2023 Issue:3 Volume:14 Page:1338-1348
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Fernández-Lainez Cynthia¹²³^ORCID,aan de Stegge Myrthe¹^ORCID,Silva-Lagos Luis Alfredo¹^ORCID,López-Velázquez Gabriel⁴,de Vos Paul¹^ORCID

Affiliation:

1. Immunoendocrinology, Division of Medical Biology, Department of Pathology and Medical Biology, University Medical Centre Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands

2. Laboratorio de Errores innatos del Metabolismo y Tamiz, Instituto Nacional de Pediatría, Av. Iman 1, 04530, Ciudad de México, Mexico

3. Posgrado en Ciencias Biológicas, Universidad Nacional Autónoma de México. Edificio D, 1° Piso. Circuito de Posgrados, Ciudad Universitaria, 04510, Ciudad de México, Mexico

4. Laboratorio de Biomoléculas y Salud Infantil, Instituto Nacional de Pediatría, Av. Iman 1, 04530, Cuidad de México, Mexico

Abstract

Dietary fibers such as fructans beneficially impact the expression of mucus- and ER stress-related genes in goblet cells (GCs) and attenuate inflammatory responses, which contributes to the knowledge of the effects of fructans on intestinal health.

Funder

Rijksuniversiteit Groningen

Universitair Medisch Centrum Groningen

Universidad Nacional Autónoma de México

Consejo Nacional de Ciencia y Tecnología

Instituto Nacional de Pediatria

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/FO/D2FO02710K