Facilely printed silk fibroin hydrogel microparticles as injectable long-lasting fillers

Author:

Xie Chunyu1,Yang Xiao1,Zheng Fan1,Shi Jiahao1,Huo Caixia2,Wang Zuyuan2,Reis Rui L.34,Kundu Subhas C.34ORCID,Xiao Bo1ORCID,Duan Lian1

Affiliation:

1. State Key Laboratory of Resource Insects, College of Sericulture, Textile, and Biomass Sciences, Southwest University, Beibei, Chongqing 400715, China

2. Beijing Green Pharmaceutical Technology Co., Ltd, Fengtai, Beijing 100070, China

3. 3Bs Research Group, I3Bs—Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Barco 4805-017, Guimaraes, Portugal

4. ICVS/3B's-PT Government Associate Laboratory, Braga, Guimarães, Portugal

Abstract

A regenerated silk fibroin hydrogel is facilely printed by a screen to obtain injectable microparticles. The microparticles possess desirable biocompatibility and lasting filling effects and have great potential for facial rejuvenation.

Funder

Venture and Innovation Support Program for Chongqing Overseas Returnees

National Natural Science Foundation of China

Science Fund for Distinguished Young Scholars of Chongqing Municipality

Jiangxi Provincial Department of Science and Technology

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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