Maternal serum lipidomics identifies lysophosphatidic acid as a predictor of small for gestational age neonates

Author:

Byeon Seul Kee12ORCID,Khanam Rasheda3,Rahman Sayedur4ORCID,Hasan Tarik4,Rizvi Syed Jafar Raza4,Madugundu Anil K.1567ORCID,Ramarajan Madan Gopal156,Jung Jae Hun128,Chowdhury Nabidul H.4ORCID,Ahmed Salahuddin4ORCID,Raqib Rubhana9,Kim Kwang Pyo8ORCID,Piazza Amy L.1ORCID,Rinaldo Piero1,Pandey Akhilesh1210ORCID,Baqui Abdullah H.3,AMANHI Bio-banking Study Group

Affiliation:

1. Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA

2. McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA

3. International Center for Maternal and Newborn Health, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA

4. Projahnmo Research Foundation, Dhaka, Bangladesh

5. Institute of Bioinformatics, International Technology Park, Bangalore 560006, India

6. Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India

7. Center for Molecular Medicine, National Institute of Mental Health and Neurosciences, Hosur Road, Bangalore, 560029, Karnataka, India

8. Department of Chemistry, Kyung Hee University, Yongin 17104, South Korea

9. Division of Infectious Diseases, International Centre for Diarrhoeal Disease Research, Bangladesh

10. Center for Individualized Medicine, Mayo Clinic, Rochester, MN 55905, USA

Abstract

Lysophosphatidic acid was found to be decreased in mothers who subsequently delivered small for gestational age neonates during 24–28 weeks of pregnancy while it was increased in mothers who delivered control neonates.

Funder

World Health Organization

Bill and Melinda Gates Foundation

The Wellcome Trust DBT India Alliance

Publisher

Royal Society of Chemistry (RSC)

Subject

Genetics,Molecular Biology,Biochemistry

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