Efficient synthesis of a library of heparin tri- and tetrasaccharides relevant to the substrate of heparanase
Author:
Affiliation:
1. State Key Laboratory of Bio-organic and Natural Products Chemistry
2. Shanghai Institute of Organic Chemistry
3. Chinese Academy of Sciences
4. Shanghai 200032, China
Abstract
A robust glycosylation protocol was fixed to construct the GlcN–(1α→4)-GlcA/IdoA linkagesen routeto heparin oligosaccharides.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/QO/C4QO00039K
Reference128 articles.
1. Heparin-Protein Interactions
2. Order Out of Chaos: Assembly of Ligand Binding Sites in Heparan Sulfate
3. Heparan sulfate: decoding a dynamic multifunctional cell regulator
4. The Structure of Glycosaminoglycans and their Interactions with Proteins
5. The Unique Antithrombin III Binding Domain of Heparin: A Lead to New Synthetic Antithrombotics
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