Changes of serum amino acid profiles by an epidermal growth factor receptor mutation and benzo[a]pyrene in mouse lung tumorigenesis

Author:

Lin Pinpin1234,Chen Yi-Rong5234,Chen Chao-Yu6784,Chang Ya-Ting6784,Chen Jhih-Sheng6784,Tsai Ming-Hsien1234,Kuo Cheng-Chin9234,Lee Hui-Ling6784

Affiliation:

1. National Institute of Environmental Health Sciences

2. National Health Research Institutes

3. Zhunan

4. Taiwan

5. Institute of Molecular and Genomic Medicine

6. Department of Chemistry

7. Fu Jen Catholic University

8. New Taipei City 24205

9. Institute of Cellular and System Medicine

Abstract

This study suggest that changes in serum amino acid profiles may be early indicators of lung tumorigenesis induced by a mutation of epidermal growth factor receptor (EGFR) and exposure to benzo[a]pyrene (BaP).

Funder

Ministry of Science and Technology, Taiwan

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Toxicology

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