Marine paralytic shellfish toxins: chemical properties, mode of action, newer analogues, and structure–toxicity relationship

Author:

Leal Joana F.1ORCID,Cristiano Maria L. S.1ORCID

Affiliation:

1. Centre of Marine Sciences (CCMAR), Department of Chemistry and Pharmacy, Faculty of Science and Technology, University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal

Abstract

This review highlights the recent findings about biotransformation in different organisms (dinoflagellates, bivalves, humans) and presents a critical revision on the latest analogues, M-toxins. A “toxicological traffic light” is also proposed.

Funder

Fundação para a Ciência e a Tecnologia

European Maritime and Fisheries Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

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