Injectable leonurine nanocrystal-loaded microspheres for long-term hyperlipidemia management

Author:

Song Zhiling1,Meng Shiyu1,Tang Zhuang1,Yang Xiaoxue1,He Yuan2,Zheng Ying2,Guo Hui3ORCID,Du Meirong14,Zhu Yizhun1,Wang Xiaolin1ORCID

Affiliation:

1. School of Pharmacy and State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macao 999078, China

2. State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau 999078, China

3. School of Chemical Engineering and Technology, Sun Yat-Sen University, Zhuhai 519082, China

4. NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai 200032, China

Abstract

Leonurine nanocrystal-loaded long-acting microspheres (Leo-nano@MP) for long-term and effective hyperlipidemia treatment in high-fat diet (HDF)-fed rats.

Funder

Macau University of Science and Technology Foundation

Natural Science Foundation of Guangdong Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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