Photoinduced homolytic decarboxylative acylation/cyclization of unactivated alkenes with α-keto acid under external oxidant and photocatalyst free conditions: access to quinazolinone derivatives

Author:

Sun Bin1234,Shi Rongcheng5234,Zhang Kesheng5234,Tang Xiaoli5234,Shi Xiayue5234,Xu Jiayun1234,Yang Jin5234,Jin Can12345ORCID

Affiliation:

1. Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals

2. Zhejiang University of Technology

3. Hangzhou

4. P. R. China

5. College of Pharmaceutical Sciences

Abstract

A green and efficient strategy for the synthesis of quinazolinone derivatives via photo-induced decarboxylative cascade radical acylation/cyclization of unactivated alkenes has been developed under oxidant and photocatalyst free conditions.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Zhejiang University of Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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