Synthesis of raspberry-like nanogapped Fe3O4@Au nanocomposites for SERS-based lateral flow detection of multiple tumor biomarkers

Author:

Shen Wanzhu12345,Wang Chongwen45367ORCID,Yang Xingsheng45367,Wang Chaoguang89103,Zhou Zihui67113,Liu Xiaoxian45367,Xiao Rui453,Gu Bing12133,Wang Shengqi12345

Affiliation:

1. Anhui Medical University

2. Hefei 410073

3. P. R. China

4. Beijing Institute of Radiation Medicine

5. Beijing 100850

6. College of Life Sciences

7. Anhui Agricultural University

8. College of Mechatronics Engineering and Automation

9. National University of Defense Technology

10. Changsha 410073

11. Hefei 230036

12. Xuzhou Medical University

13. Xuzhou 221004

Abstract

A novel magnetic SERS-LFA system with raspberry-like Fe3O4@Au MNPs as nanogapped SERS tags was proposed for the quantitative and ultra-sensitive detection of multiple tumor biomarkers in biological samples.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Anhui Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry

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