Liquid droplets of protein LAF1 provide a vehicle to regulate storage of the signaling protein K-Ras4B and its transport to the lipid membrane-Reference-Cited by-同舟云学术

Liquid droplets of protein LAF1 provide a vehicle to regulate storage of the signaling protein K-Ras4B and its transport to the lipid membrane

Published:2021 Issue:9 Volume:23 Page:5370-5375
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Li Lei¹²³⁴⁵,Herzog Marius¹²³⁴⁵,Möbitz Simone¹²³⁴⁵,Winter Roland¹²³⁴⁵^ORCID

Affiliation:

1. Faculty of Chemistry and Chemical Biology

2. Physical Chemistry I - Biophysical Chemistry

3. TU Dortmund University

4. 44227 Dortmund

5. Germany

Abstract

We found that membrane-less protein condensates, such as of P-granule protein LAF1, are able to provide an additional vehicle to regulate storage and transport of membrane-associated signaling proteins such as K-Ras4B to the lipid membrane.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CP/D1CP00007A

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