Antibodies, repertoires and microdevices in antibody discovery and characterization

Author:

Schlotheuber Luca Johannes1,Lüchtefeld Ines12ORCID,Eyer Klaus1ORCID

Affiliation:

1. ETH Laboratory for Functional Immune Repertoire Analysis, Institute of Pharmaceutical Sciences, D-CHAB, ETH Zürich, 8093 Zürich, Switzerland

2. ETH Laboratory for Tumor and Stem Cell Dynamics, Institute of Molecular Health Sciences, D-BIOL, ETH Zürich, 8093 Zürich, Switzerland

Abstract

Essential in treating numerous diseases, novel therapeutic antibody candidates are needed. This critical review examines recent advances in microdevices and the challenges associated with candidate discovery and characterization.

Funder

H2020 European Research Council

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

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