Shear-induced endothelial NOS activation and remodeling via heparan sulfate, glypican-1, and syndecan-1-Reference-Cited by-同舟云学术

Shear-induced endothelial NOS activation and remodeling via heparan sulfate, glypican-1, and syndecan-1

Published:2014 Issue:3 Volume:6 Page:338-347
ISSN:1757-9694
Container-title:Integr. Biol.
language:en
Short-container-title:Integr. Biol.

Author:

Ebong Eno E.¹²³⁴⁵,Lopez-Quintero Sandra V.¹²³,Rizzo Victor⁶⁷⁸,Spray David C.¹²³,Tarbell John M.⁴⁵⁹

Affiliation:

1. Department of Neuroscience

2. Albert Einstein College of Medicine

3. Bronx, USA

4. Department of Biomedical Engineering

5. City College of New York

6. Cardiovascular Research Center

7. Temple University School of Medicine

8. Philadelphia, USA

9. New York, USA

Abstract

This work uncovers new mechanisms of endothelial cell glycocalyx mediated conversion of fluid forces into diverse biomolecular and biomechanical responses, such as caveola associated signaling and cytoskeleton reorganization.

Funder

National institute of Health and Medical Research

Publisher

Oxford University Press (OUP)

Subject

Biochemistry,Biophysics

Link

http://pubs.rsc.org/en/content/articlepdf/2014/IB/C3IB40199E

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4. The role of the glycocalyx in reorganization of the actin cytoskeleton under fluid shear stress: A "bumper-car" model

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