A multiplatform metabolomics approach for comprehensive analysis of GIST xenografts with various <i>KIT</i> mutations-Reference-Cited by-同舟云学术

A multiplatform metabolomics approach for comprehensive analysis of GIST xenografts with various KIT mutations

Published:2023 Issue:16 Volume:148 Page:3883-3891
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Macioszek Szymon¹^ORCID,Dudzik Danuta¹,Biesemans Margot¹^ORCID,Wozniak Agnieszka²,Schöffski Patrick²,Markuszewski Michal J.¹^ORCID

Affiliation:

1. Department of Biopharmaceutics and Pharmacodynamics, Medical University of Gdańsk, Hallera 107, 80-416 Gdańsk, Poland

2. Laboratory of Experimental Oncology, Department of Oncology, KU Leuven, and Department of General Medical Oncology, University Hospitals Leuven, Leuven Cancer Institute, Leuven, Belgium

Abstract

Metabolomics is a promising tool for studying the impact of mutations or treatments on GIST tissue. We found that parallel GC-MS and RP-LC-MS analyses allow one to obtain a comprehensive global picture of the GIST metabolome.

Funder

Narodowe Centrum Nauki

European Social Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/AN/D3AN00599B

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