Seleno-relaxin analogues: effect of internal and external diselenide bonds on the foldability and a fibrosis-related factor of endometriotic stromal cells-Reference-Cited by-同舟云学术

Seleno-relaxin analogues: effect of internal and external diselenide bonds on the foldability and a fibrosis-related factor of endometriotic stromal cells

Published:2024 Issue:8 Volume:5 Page:729-737
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

Satoh Yuri¹,Ono Yosuke²,Takahashi Rikana¹,Katayama Hidekazu³,Iwaoka Michio¹⁴^ORCID,Yoshino Osamu²,Arai Kenta¹⁴^ORCID

Affiliation:

1. Department of Chemistry, School of Science, Tokai University, Kitakaname, Hiratsuka-shi, Kanagawa 259-1292, Japan

2. Department of Obstetrics and Gynecology, University of Yamanashi, 1110 Shimokato, Chuo-shi, Yamanashi 409-3898, Japan

3. Department of Bioengineering, School of Engineering, Tokai University, Kitakaname, Hiratsuka-shi, Kanagawa 259-1292, Japan

4. Institute of Advanced Biosciences, Tokai University, Kitakaname, Hiratsuka-shi, Kanagawa 259-1292, Japan

Abstract

The [C11UA,C11UB] and [C10UA,C15UA] variants of human relaxin-2, which were synthesized via a one-pot assembly of the component A- and B-chains, efficiently reduced the expression of a tissue fibrosis-related factor in endometriotic stromal cells.

Funder

Japan Society for the Promotion of Science

Promotion and Mutual Aid Corporation for Private Schools of Japan

Tokai University

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CB/D4CB00095A

Reference80 articles.

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5. Relaxin’s Physiological Roles and Other Diverse Actions