A versatile and high-throughput flow-cell system combined with fluorescence imaging for simultaneous single-molecule force measurement and visualization

Author:

Zou Zhenyu12,Liang Jialun12,Jia Qian3ORCID,Bai Di4,Xie Wei3,Wu Wenqiang4,Tan Chuang12,Ma Jie12ORCID

Affiliation:

1. School of Physics, Sun Yat-sen University, Guangzhou 510275, P.R. China

2. State Key Laboratory of Optoelectronic Materials and Technologies, Sun Yat-sen University, Guangzhou 510275, P.R. China

3. MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, Guangdong, 510006, P.R. China

4. School of Life Sciences, State Key Laboratory of Crop Stress Adaptation and Improvement, Henan University, Kaifeng 475001, P.R. China

Abstract

A fully calibrated high-throughput flow-cell system combined with fluorescence microscopy can simultaneously measure single-molecule forces and images.

Funder

Sun Yat-sen University

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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