Polymer-augmented liposomes enhancing antibiotic delivery against intracellular infections
Author:
Affiliation:
1. Department of Bioengineering
2. University of Washington
3. Seattle
4. USA
5. Division of Pulmonary and Critical Care Medicine
6. Harborview Medical Center
Abstract
A simplified liposome formulation with three functionalities to enhance antibiotic bioavailability to cytosolic bacteria: carbohydrate-mediated targeting; pH-responsive release; endosomal-release activity.
Funder
Defense Threat Reduction Agency
National Institutes of Health
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering
Link
http://pubs.rsc.org/en/content/articlepdf/2018/BM/C8BM00282G
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