A Trp-BODIPY cyclic peptide for fluorescence labelling of apoptotic bodies

Author:

Subiros-Funosas Ramon1234,Mendive-Tapia Lorena5678,Sot Jesus91011128,Pound John D.1234,Barth Nicole1234,Varela Yaiza91011128,Goñi Felix M.91011128,Paterson Margaret1234,Gregory Christopher D.1234,Albericio Fernando567813,Dransfield Ian1234,Lavilla Rodolfo13147815,Vendrell Marc1234ORCID

Affiliation:

1. MRC/UoE Centre for Inflammation Research

2. The University of Edinburgh

3. EH16 4TJ Edinburgh

4. UK

5. Department of Inorganic and Organic Chemistry

6. University of Barcelona

7. 08028 Barcelona

8. Spain

9. Instituto Biofisika (CSIC, UPV/EHU) and Departamento de Bioquimica

10. Universidad del País Vasco

11. Campus de Leioa

12. 48940 Leioa

13. CIBER-BBN

14. Networking Centre on Bioengineering, Biomaterials and Nanomedicine

15. Laboratory of Organic Chemistry

Abstract

We describe the synthesis and characterization of a Trp-BODIPY fluorogenic peptide for labelling subcellular bodies released by human apoptotic cells.

Funder

Bloodwise

Medical Research Council

Generalitat de Catalunya

Biotechnology and Biological Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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