Electro-induced O–S bonding reaction targeting biological macromolecules

Author:

Jiang Shuqiang1,Xiao Longyu1,Pan Li2,Huang Qiaoyu3,Huo Fujin1,Gao Meng1ORCID,Lu Cuifen1ORCID,Wu Pan2,Weng Yue1ORCID

Affiliation:

1. Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecule, State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Chemistry and Chemical Engineering, Hubei University, Wuhan, P. R. China

2. State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, 430062, P. R. China

3. Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Key Laboratory of Polymer Materials, School of Materials Science and Engineering, Hubei University, Wuhan, 430062, P. R. China

Abstract

This study endeavors to explore the utilization of aromatic sulfinates as bioconjugation handles, addressing the challenges associated with the modification of Tyrosine and paving the way for innovative approaches to biomolecule functionalization.

Funder

Key Laboratory for the Synthesis and Application of Organic Functional Molecules, Ministry of Education

National Natural Science Foundation of China

State Key Laboratory of Biocatalysis and Enzyme Engineering

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

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