Self-driven immune checkpoint blockade and spatiotemporal-sensitive immune response monitoring in acute myeloid leukemia using an all-in-one turn-on bionanoprobe

Author:

Zhang Dangui12,Wu Honglian3,Wang Tianci1,Wang Yuting1,Liu Sixi1,Wen Feiqiu1,Oudeng Gerile1ORCID,Yang Mo3ORCID

Affiliation:

1. Department of Hematology and Oncology, Shenzhen Children's Hospital of Shantou University Medical College, Futian, Shenzhen, Guangdong, 518026, P. R. China

2. Research Center of Translational Medicine, Second Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, 515041, P. R. China

3. Department of Biomedical Engineering, Hong Kong Polytechnic University, Hung Hom, Kowloon, 999077, Hong Kong SAR, P. R. China

Abstract

An all-in-one bionanoprobe was developed for self-driven immune checkpoint blockade and spatiotemporal-sensitive immune response monitoring in heterogeneous acute myeloid leukemia cells.

Funder

National Natural Science Foundation of China

Shenzhen Science and Technology Innovation Program

Guangdong Medical Research Foundation

Research Grants Council, University Grants Committee

Hong Kong Polytechnic University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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