LWJ-M30, a conjugate of DM1 and B6, for the targeted therapy of colorectal cancer with improved therapeutic effects-Reference-Cited by-同舟云学术

LWJ-M30, a conjugate of DM1 and B6, for the targeted therapy of colorectal cancer with improved therapeutic effects

Published:2023 Issue:16 Volume:13 Page:10840-10846
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Zhang Qiu-Yan¹^ORCID,Yu Qing-Long¹,Luan Wei-Jing¹,Li Tong-Fang¹,Xiao Ya-Ni¹,Zhang Li¹,Li Yi¹,Rong Rong¹,Ren Chun-Guang¹²

Affiliation:

1. Yantai Key Laboratory of Nanomedicine & Advanced Preparations, Yantai Institute of Materia Medica, Shandong, China

2. College of Life Sciences, Yantai University, Yantai 264005, China

Abstract

LWJ-M30 targeted TfR, dramatically decreased the level of polymeric tubulin, while the disruption of microtubules meant the cell cycle was arrested in the G2/M phase and thus caused cells apoptosis.

Funder

Yantai Science and Technology Bureau

Natural Science Foundation of Shandong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D2RA07758B

Reference40 articles.

1. Novel Diagnostic Biomarkers in Colorectal Cancer

2. Pathological Features and Prognostication in Colorectal Cancer

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4. A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors, Development, Symptoms and Diagnosis

5. Assessing Individual Risk for High-Risk Early Colorectal Neoplasm for Pre-Selection of Screening in Shanghai, China: A Population-Based Nested Case–Control Study

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