Unravelling microRNA regulation and miRNA–mRNA regulatory networks in osteogenesis driven by 3D nanotopographical cues

Author:

Balachander Gowri Manohari1ORCID,Nilawar Sagar2,Meka Sai Rama Krishna2,Ghosh Lopamudra Das2ORCID,Chatterjee Kaushik2ORCID

Affiliation:

1. School of Biomedical Engineering, Indian Institute of Technology (BHU) Varanasi, Varanasi-221005, India

2. Department of Materials Engineering, Indian Institute of Science, Bangalore-560012, India

Abstract

The figure depicts how osteo-inductive factors and 3D nanotopographical cues on a fibrous substrate activate a stimuli-specific set of mRNA–miRNA gene regulatory networks apart from a core set of networks to bring into effect stem cell osteogenesis.

Funder

Department of Science and Technology, Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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