A polyhexamethylene biguanide-assembly assisted strategy of dentin bonding greatly promotes bonding effects and caries treatment

Author:

Shu Chang1ORCID,Chen Yadong1,Zhang Zhenzhen1ORCID,Lei Yuqing1,Xu Jiajia1,Lao Weiwei1ORCID,Xi Qingping1,Sun Qiang1,Li Xiaojun1,Liao Hongbing2,Luo Qiaojie1ORCID,Li Xiaodong1ORCID

Affiliation:

1. Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou 310000, P. R. China

2. Guangxi Key Laboratory of Oral and Maxillofacial Rehabilitation and Reconstruction, College of Stomatology, Guangxi Medical University, Nanning 530021, P. R. China

Abstract

By a one-step 30s treatment of polyhexamethylene biguanide (PHMB), residual bacteria in remaining caries-affected dentin are killed, and an intrinsic antibacterial defect-low hybrid layer is constructed, promoting bonding effect and caries treatment.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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